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"Route 666"

DEAN REUNITES WITH HIS FIRST LOVE ─ Dean (Jensen Ackles) is contacted by his first love Cassie (Megalyn Echikunwoke), an African-America girl, who asks him to come to Mississippi to investigate a string of racially motivated murders. Each murder is linked to a mysterious truck that seems to have no driver and leave no tracks. Sam (Jared Padalecki) is stunned to see this new side of his brother as Dean struggles to come to grips with the residual feelings he has for Cassie. The episode was written by Eugenie Ross-Leming & Brad Buckner and directed by Paul Shapiro (#112).